What is Tumor Necrosis Factor Receptor Associated Periodic Syndrome (TRAPS)?
TRAPS is an inherited and rare condition belonging to a group of diseases called Periodic Fever Syndromes. Like other types of Periodic Fevers, TRAPS is an autoinflammatory condition that can cause attacks or flares.
What causes TRAPS?
TRAPS is an inherited disease that is caused by the genetic mutation of the TNFRSF1A (Tumor Necrosis Factor Receptor Super Family 1A) gene. When this happens, it can lead to inflammation and other TRAPS symptoms.
How long will my child have TRAPS?
There is no cure for TRAPS, but with continuous treatment, children with TRAPS may experience symptom improvement.
What are Periodic Fever Syndromes?
Periodic Fever Syndromes are a group of rare, autoinflammatory diseases characterized by a range of symptoms, including but not limited to recurrent fevers, rash, pain, and joint inflammation. Periodic Fevers are typically inherited from family members, but can occur on their own. Periodic Fevers can affect both children and adults, though symptoms usually begin during childhood.
Is TRAPS contagious?
TRAPS is not contagious. It's an inherited disease, which means that it can be passed down from family members, although the disease can occur on its own. Certain factors are thought to trigger TRAPS flares, including stress, minor trauma, and exercise.
What will happen to my child with TRAPS?
TRAPS can vary from child to child. You should keep track of your child's TRAPS symptoms, and be sure to know about possible disease triggers. Learn about TRAPS treatment options.
What is ILARIS?
ILARIS® is a prescription medication that is FDA approved to treat TRAPS. ILARIS works by attaching to and blocking interleukin-1 beta (IL-1β), a type of cytokine responsible for inflammation. For TRAPS, ILARIS is given once a month as a subcutaneous injection right below the skin.
How can ILARIS help with TRAPS?
ILARIS helps provide fast and sustained relief from TRAPS. In a study of 22 patients with TRAPS, 45.5% had minimal to no disease activity at Day 15 through Week 16. Study participants were assessed for their CRP measurements and given a single Physician's Global Assessment (PGA) score based on several signs and symptoms, including: skin rash, musculoskeletal pain, abdominal pain, and eye manifestations.
Is ILARIS given intravenously?
ILARIS is not given as an intravenous infusion (infused inside a vein over a period of time). Instead, it is given as a subcutaneous (right under the skin) injection, by a doctor or nurse. A home health nurse can be sent to your home to administer ILARIS to your child. If you are eligible, this service and other ILARIS support options may be available for your child.
Is support available to help us pay for ILARIS?
We're committed to helping you get access to ILARIS. Our ILARIS Companion representatives are here to help by working with your doctor or your child's doctor, and:
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Contacting your insurance company
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Verifying insurance benefits and investigation of coverage
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Addressing coverage issues
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Navigating prior authorization and appeals, if needed
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Providing co-pay* assistance for eligible patients with commercial insurance
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Providing information about alternative assistance options for uninsured patients
*Limitations apply. Please contact ILARIS Companion at 866-972-8315 for more information.
Whom should I speak to if I have more questions about ILARIS?
Talk to your rheumatologist, or your child's pediatric rheumatologist or other healthcare professional. A TRAPS treatment team can consist of many important members. Make sure that you find a doctor that you are both comfortable with.
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