Glossary

A – Z

Z – A

Print HIDS glossary terms
  • Autoinflammatory disease:

    an illness in which the body's control of inflammation is not functioning properly, leading to uncontrolled inflammation.

  • Biologic:

    a product made from living cells that is used to treat diseases.

  • Cytokine:

    a protein produced by the body that interacts with the cells of the immune system to help fight infection. When the body produces too much of a cytokine, it can cause inflammation and tissue destruction.

  • Disease:

    a condition of a body part, organ, or system that occurs due to genetics, infection, or the environment and that typically presents with a specific group of symptoms.

  • Familial Mediterranean Fever:

    a rare and chronic autoinflammatory disease belonging to a group of diseases known as Periodic Fever Syndromes.

  • Flare:

    the worsening and increase in severity of disease symptoms.

  • Hyperimmunoglobulin D Syndrome / Mevalonate Kinase Deficiency:

    an inherited, rare, and serious condition belonging to a group of diseases called Periodic Fever Syndromes.

  • Immune system:

    the body's natural defense system that protects against any material foreign to the body.

  • Inflammation:

    the body's protective response that results in heat, pain, redness, and swelling.

  • Injection:

    usually referred to as “a shot,” an injection puts medication into the body using a syringe.

  • Interleukin-1 beta (IL-1β):

    a type of cytokine that plays a key role in the body's inflammatory response.

  • Pediatric rheumatologist:

    a doctor who specializes in treating children and adolescents with rheumatic diseases, including arthritis, many autoimmune diseases, and many autoinflammatory diseases.

  • Periodic Fever Syndromes:

    a group of rare, autoinflammatory diseases characterized by a range of symptoms including recurrent fevers, rash, pain, and joint inflammation.

  • Symptoms:

    a description of the way you are feeling due to an illness.

  • Tumor Necrosis Factor Receptor Associated Periodic Syndrome (TRAPS):

    an inherited, rare, and serious condition belonging to a group of diseases called Periodic Fever Syndromes.