Dosing for ILARIS to Treat FMF

Dosing for ILARIS to Treat FMF
Dosing for ILARIS to Treat FMF

A once-monthly injection

ILARIS is not given as an intravenous infusion (infused inside a vein over time); it is given as a subcutaneous injection (right under the skin) once a month by a doctor or nurse.

At your doctor's request, Novartis can send a home health nurse to your home to give your child his or her monthly ILARIS injection.

How Does ILARIS Work?

To understand how ILARIS works, it's important to start with the role of the immune system in Familial Mediterranean Fever (FMF), and how inflammation gets triggered in the body.

Inflammation with FMF

Inflammation with FMF

Inflammation with FMF

Inflammation with FMF

ILARIS targets an important cause of FMF symptoms

  • For children with FMF, the immune system (the body's natural defense system that protects against "foreign" invaders) produces too much of a substance called a cytokine

  • Too much of a cytokine called interleukin-1 beta (IL-1) is an important cause of inflammation in FMF. When IL-1 attaches to interleukin-1 receptors (IL-1R), the immune system triggers inflammation

  • For children with FMF, the immune system triggers inflammation even when there's no infection to fight. This can cause recurring FMF symptoms, like fever and swollen and/or painful joints

FMF Treatment with ILARIS

Treatment with ILARIS

FMF Treatment with ILARIS

Treatment with ILARIS

ILARIS targets IL-1 to help reduce inflammation

ILARIS targets IL-1 to help reduce inflammation

  • ILARIS is a different kind of treatment for FMF. It's a biologic medicine, which means it's designed to target a specific source of inflammation. ILARIS targets IL-1

  • By attaching to IL-1, ILARIS helps to block its interaction with IL-1R

  • This action helps to stop the immune system from triggering inflammation

If your child is diagnosed with FMF, ask a doctor whether ILARIS may be right for your child.

Next: Talking to a Doctor